Infección por el SARS-CoV-2 en pacientes hipertensos, revisión no sistemática

Nilvia Bienvenida Serrano Gámez, Rolando Teruel Ginés, Alejandro Jesús Bermúdez Garcell, María de los Angeles Leyva Montero

Texto completo:

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Resumen

Introducción:

La hipertensión arterial es la comorbilidad cardiovascular más prevalente, en los pacientes infectados, por la COVID-19.

Objetivo:

Describir los mecanismos de la hipertensión arterial, con la gravedad de la infección viral por SARS-CoV-2.

Métodos:

Las bases de datos seleccionadas fueron: PubMed, Scientific Electronic Library Online, Scielo y Google Académico. Se realizó una revisión independiente y se propusieron 50 referencias. No se pusieron restricciones en cuanto al tipo de trabajo, en idioma español e inglés. Se seleccionaron 44 referencias de la propuesta inicial, por mayoría simple.

Conclusiones:

La hipertensión arterial aumenta el riesgo de hospitalización y muerte, por la COVID-19. Se explica la enfermedad e infección por SARS-CoV-2 que coexiste con la hipertensión, entre los que se destacan el papel de la enzima convertidora de angiotensina 2, los trastornos del sistema renina-angiotensina-aldosterona, la disfunción inmune con excesiva inflamación y la disfunción gastrointestinal. 

Palabras clave

SARS-CoV-2; COVID-19 grave; hipertensión arterial; enzima convertidora de angiotensina 2; sistema renina-angiotensina-aldosterona; fármacos antihipertensivos.

Referencias

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Copyright (c) 2023 Nilvia Bienvenida Serrano Gámez, Rolando Teruel Ginés, Alejandro Jesús Bermúdez Garcell, María de los Angeles Leyva Montero

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