Correlation clinic- imagenological of brain lesions on neonates though magnetic resonance

Authors

Keywords:

magnetic resonance imaging, neonates, neurological sequelae

Abstract

Introduction: Magnetic resonance provides a study of brain architecture and myelination, it is a tool in the evaluation of neurodevelopment.

Objective: To describe the correlation between neurological sequelae and images, using magnetic resonance imaging, in neonates.

Methods: An observational, prospective, multicenter study was carried out from January 2016 to December 2019, at the General Calixto García¨ University Hospital, with the collaboration of the Comandante Manuel Piti Fajardo¨ Hospital. The study population was 15 newborns. The variables included were: sex, birth weight, gestational age, type of delivery, types of depression, patterns of injury and neurological sequelae. In the statistical analysis, the Chi Square of Mantel and Haenszel was used.

Results: 53.3% of the neonates were male, 66.7 % were born by dystocia and were low weight, 60 % were preterm. Severe neonatal depression prevailed with 53.3 %, white matter hypersignal lesion was diagnosed in 26.7 %. In preterm infants, hydrocephalus, language and attention disorders prevailed in 20 %. In term children, cerebral palsy in 26.7 % and epilepsy in 13.3 %.

Conclusions: Neonates are characterized by being male, preterm, low birth weight, born by dystocia and neonatal depression. Injury patterns in term neonates are correlated with cerebral palsy and epilepsy, in preterms with hydrocephalus, language and attention disorders.

Downloads

Download data is not yet available.

Author Biographies

Gretel Fernández Núñez, Hospital Ginecoobstetrico de Guanabacoa

Especialista de II grado en Neonatología y de I grado en Medicina General Integral. Máster en Atención Integral al niño. Profesor asistente Investigador agregado. Hospital Gineco-obstétrico de Guanabacoa

José Manuel Inclán Llanes, Hospital Universitario General “Calixto García”

Especialista de I grado en Imagenología y de I grado en Medicina General Integral. Máster en Medios Diagnósticos. Profesor asistente

References

Gleason CA, Juul SE. Enfermedades del recién nacido. Back AS, Miller PS. Lesión cerebral en el recién nacido prematuro. Barcelona: Elsevier España; 2019. p.879-85.

Valdés Armenteros R. Examen clínico al recién nacido [Internet]. 2.ed. La Habana: Editorial Ciencias Médicas; 2016. [citado 19 Ago 2022]. Disponible en: http://www.bvscuba.sld.cu/libro/examen-clinico-al-recien-nacido-2da-ed/

Valdés Armenteros R, Ruiz Tellechea Y, Morilla Guzmán A, Domínguez Dieppa F, Díaz Álvarez M, Montes López E, et al. Neonatología. Diagnóstico y tratamiento [Internet].2. d. La Habana. Editorial Ciencias Médicas; 2016. [citado 19 Ago 2022]. Disponible en: http://www.bvscuba.sld.cu/libro/neonatologia-diagnostico-y-tratamiento-2da-ed/ .

Espiritu Rojas ER. Intraventricular hemorrhage in premature infants under 28 weeks in general hospital of Lima, 2013 - 2017. Acta Med Peru [Internet]. 2021 Abr [citado 19 Ago 2022];38(1):7-16. Disponible en: https://amp.cmp.org.pe/index.php/AMP/article/view/1921

Counsell SJ, Rutherford MA, Cowan FM. Magnetic resonanc imaging of preterm brain injury. Arch Dis Child Fetal Neonatal [Internet].2003 [citado 9 Jun 2022]; 88(4):269-74. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1721585/

Gale C, Jeffries S, Logan KM, Chappell KE, Uthaya S.N, Modi N. Avoiding sedation in reseach MRI and spectroscopy in infants: our approach, success rate and prevalence of incidental findings. Arch Dis Child Fetal Neonatal. [Internet]. 2013 [citado 12 jun 2022];98(3):267-8. Disponible en: https://fn.bmj.com/content/98/3/F267.long

Vargas Vaca Y, Devia C, Berlotto AM, Suarez Obando F. Caracterización de los recién nacidos con asfixia perinatal moderada o severa manejados con hipotermia cerebral selectiva en la unidad de recién nacidos del Hospital Universitario San Ignacio desde junio de 2015 hasta marzo de 2017. Univ Med [Internet]. 2019 Dec [citado 19 Ago 2022]; 60(4): 4-13. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S2011-08392019000400004&lng=en

Groenendaal F, de Vries LS, Groenendaal F. Fifty years of brain imaging in neonatal encephalopathy following perinatal asphyxia. Pediatr Res Internet]. 2017[citado 18 Mar 2022];81(1-2):150-5. Disponible en: https://www.nature.com/articles/pr2016195

Inclan-Llanes J. Primer reporte de aplicación de la Resonancia Magnética sin sedación en neonatos. Archivos del Hospital Universitario ¨General Calixto García¨ [Internet]. 2017 [citado 19 Ago 2022];4(3):[aprox. 7 p.]. Disponible en: http://www.revcalixto.sld.cu/index.php/ahcg/article/view/153

Motta-Ramírez GA, Jiménez-Parra JL, Limas-Santos NI, Álvarez-Flores NH, Del Carmen Solis-Vargas M. El uso y abuso de la tomografía computarizada de cráneo en la consulta externa pediátrica neurológica. Rev Mex Neuroci Internet]. 2011 [citado 11 Jun 2020];12(6):358-64. Disponible en: https://www.medigraphic.com/pdfs/revmexneu/rmn-2011/rmn116e.pdf

Boardman JP, Counsell SJ. Invited review: factors associated witch atpycal brain development in preterm infants: insights from magnetic resonance imaging. Neuropathology and Applied Neurology [Internet]. 2020 [citado 25 Jun 2022];46(5):413-21. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496638/pdf/NAN-46-413.pdf

Dunne JM, Wertheim D, Clarke P, Kapellou O, Chisholm P, Boardman JP, et al. Automated electroencephalographic discontinuity in cooled newborns predicts cerebral MRI and neurodevelopmental outcome. Arch Dis Child Fetal Neonatal[Internet]. 2017 [citado 19 Jun 2022];102(1):58-64. Disponible en: https://fn.bmj.com/content/102/1/F58.long

Romero Guzman, GJ. López Muñoz. F. Prevalenc and risk factors for periventricular leukomalacia in preterm infants. A systematic review. Rev Neurol [Internet]. 2017 [citado 4 Jul 2020];65: 57-62. Disponible en: https://www.neurologia.com/articulo/2017002/eng

Sarkar S, Shankaran S, Barks J, Do BT, Laptook AR, Das A, et al. Outcome of preterm infants with trasient cystic periventricular leukomalacia on serial cranial imaging up to term equivalent age. J Pediatric [Internet]. 2018[citado 4 Jul 2022]; 195:59–65e3. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407628/

Experiencia en Cuba. En: Álvarez Fumero RT, Torres Sánchez M, Padrón Vera EM. Guía de actuación para la atención al parto respetuoso [Internet]. La Habana. Editorial Ciencias Médicas; 2022. p.2-6. [citado 4 Jul 2022]. Disponible en: http://bvs.sld.cu/libros/guia_actuacion_atencion_parto_respetuoso/guia_actuacion_atencion_parto_respetuoso_experiencias_cuba.pdf

Franco Argote O, Coca Álvarez G, Domínguez Dieppa F, Andrés amador D, Andino Almeida D. La encefalopatía Hipoxico isquémica en una unidad de cuidados intensivos. Revista Cubana de Pediatría. [Internet].2017 [citado 8 Jun 2022];89(4):1-11. Disponible en: http://www.revpediatria.sld.cu/index.php/ped/article/view/339

Chilipio Chiclla MA, Atencio Castillo KE, Santillán Árias JP. Predictores perinatales de Apgar persistentemente bajo a los 5 minutos en un hospital peruano. Revista de la Facultad de Medicina Humana [Internet].2021 [citado 8 Jul 2022];21(1):40-9. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S2308-05312021000100040

Back SA. White matter injury in the preterm infant: pathology and mechanisms. Acta Neuropathol [Internet]. 2017 [citado 8 Jul 2020];134(3):331-49. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973818/

Pappas A, Chapman-Adams I, Shankaran S, McDonald SA, Stoll J, Laptook Abbot R, et al. Neurodevelopmental and behavior outcomes in extremely premature neonates with ventriculomegaly in the absence of periventricular-intraventricular hemorrhage. Jama Pediatric [Internet]. 2018[citado 6 Jul 2020];172(1):32-42. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833521/?report=printable

Heinz ER, Provenzale JM. Imaging findings in neonatal hypoxia: a practical review. AJR Am J Roentgenol [Internet].2009[citado 12 Jun 2020];192(1):41–7. Disponible en: https://www.ajronline.org/doi/10.2214/ajr.08.1321

Downloads

Published

2022-09-07

How to Cite

1.
Fernández Núñez G, Inclán Llanes JM. Correlation clinic- imagenological of brain lesions on neonates though magnetic resonance. Medimay [Internet]. 2022 Sep. 7 [cited 2024 Nov. 2];29(3):427-36. Available from: https://revcmhabana.sld.cu/index.php/rcmh/article/view/2188

Issue

Vol. 29 No. 3 (2022)

Section

ORIGINAL ARTICLES

License

Medimay protects copyright from the very first moment the submission is made, but upon publication it assumes a Creative Commons 4.0 (cc-by-nc) license, which allows the use of the work to share (copy and redistribute the material in any medium or format) and adapt (remix, transform and build from the material) as long as exclusive mention is made of the publication in the journal as a primary source, prohibiting its commercialization. The author always retains his/her right.

Most read articles by the same author(s)