Pathophysiological mechanisms of COVID-19 on the nervous system

Authors

Keywords:

SARS-Cov-2, COVID -19, pathophysiology, neurological and cognitive manifestations

Abstract

Introduction:

Currently, it is clearly known that the manifestations of COVID -19 cover a wide range of neurological disorders, which are not yet well understood.

Objectives:

Exposing the main types of neurological and cognitive alterations associated with COVID-19.

Methods:

A systematic review was carried out in the PubMed and Google Scholar databases. Articles with free access to the full text, published in Spanish or English, were included. Duplicate studies and those with low scientific quality were excluded; they were evaluated through critical and specialized reading. 48 articles were referenced.

Conclusions:

The invasion routes of SARS-CoV-2, postulated so far, are hematogenous and transneuronal. Pathophysiological theories involve different mechanisms. There are several neurological and cognitive alterations associated with COVID-19.

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Author Biographies

Erie Rafael Roche González, Instituto de Ciencias Básicas y Preclínicas “Victoria de Girón”.La Habana.

Médico General. Instructor .Instituto de Ciencias Básicas y Preclínicas “Victoria de Girón”.La Habana.

Judith Cabrera González, Hospital General Docente “Leopoldito Martínez”.San José de Las Lajas. Mayabeque.

Especialista de I y II gradob en Fisiología Normal y Patológica. Investigadora y Profesora Auxiliar.Hospital General Docente “Leopoldito Martínez”.Facultad de Ciencias Médicas Mayabeque.

Yissel Amaeijeiras Galbán, Hospital General Docente “Leopoldito Martínez”.San José de Las Lajas. Mayabeque.

Especialista de I grado en Neurología.Hospital General Docente “Leopoldito Martínez”. San José de Las Lajas. Mayabeque.

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Published

2023-10-19

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1.
Roche González ER, Cabrera González J, Amaeijeiras Galbán Y. Pathophysiological mechanisms of COVID-19 on the nervous system. Medimay [Internet]. 2023 Oct. 19 [cited 2024 Nov. 4];30(3):332-4. Available from: https://revcmhabana.sld.cu/index.php/rcmh/article/view/1965

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Vol. 30 No. 3 (2023)

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REVIEW ARTICLES

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